Stability of urine ethyl glucuronide
Stability of urine ethyl glucuronide
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Issue Date
2008
Authors
Prince, Teri R.
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Abstract
The detection of ethyl glucuronide (EtG) in urine samples is an important tool for monitoring the compliance of offenders on probation. As a non-volatile, water-soluble, direct metabolite of ethanol, it has become one of the fastest emerging biomarkers for proof of alcohol consumption. This investigation was conducted to: insure that urine samples positive for EtG remained stabile at room temperature for up to 10 days; to discover whether or not the type of alcohol consumed affects EtG stability; and finally, if EtG is spontaneously produced in negative samples that are stored at room temperature for 10 days. Subjects included 6 volunteers asked to consume mixed drinks, 6 volunteers asked to consume wine, 6 volunteers asked to consume beer, and 6 volunteers asked to abstain from alcohol consumption for 7 days. The last 6 volunteers were broken into 2 groups. One group of 3 was asked to avoid any products containing ethyl alcohol, such as vanilla, certain mouthwashes, soaps, and deodorants. The other 3 were allowed to continue use of these products. All 24 volunteers provided 80mLs of midstream urine to be monitored, through duplicate quantitative testing by GCMS, for a 10 day period while being stored at room temperature.
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Forensic sciences