An Exploration on the Efficacy of MDMA-Assisted Therapy in the Treatment of Eating Disorders
An Exploration on the Efficacy of MDMA-Assisted Therapy in the Treatment of Eating Disorders
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Issue Date
2025-04-28
Authors
Qu, Qrystal
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Abstract
This capstone project investigates the potential of methylenedioxymethamphetamine (MDMA)-assisted therapy as a novel approach for treatment-resistant eating disorders. In light of clinical and theoretical research on trauma, as well as neuroscience and psychedelic studies, it discusses how MDMA may alleviate eating disorder symptoms through modulating serotonin signaling, oxytocin levels, and amygdala hyperactivity. The review integrates current knowledge on the nature of eating disorders, the shortcomings of traditional treatments, and the link between trauma and eating disorders. The preliminary findings from post-traumatic stress disorder (PTSD) studies, where the patients reported decreases in secondary eating disorder symptoms after receiving MDMA-assisted therapy, provide evidential backing. The therapeutic approach is described as combining humanistic aspects with a trauma-informed approach focused on eating disorders. Despite these questions, MDMA has the potential to target maintaining factors that traditional therapies cannot effectively change and may provide new relief for the 20-30% of patients who fail standard treatments.
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Keywords
MDMA-assisted therapy , eating disorders , treatment-resistant